Types of Inherited Colon Cancer
Colon cancer is increasingly common. There will be about 125,000 new cases diagnosed in the United States this year. Many of these cases were in people over 50 years and are random. A small percentage, about 10%, but it's a coincidence that they have a hereditary form of colon cancer. It may be four different hereditary conditions, hereditary non-polyposis colon cancer, familial adenomatous represent, represent young people caused(can also be hereditary) and Peutz-Jegher's.
Colon cancer is caused by damage to genes in cells of the colon. This can cause damage to cells to grow freely. This unrestricted growth becomes a polyp, which will become cancerous if not removed. Usually it takes a long time for polyps to develop and even longer to become cancer. Which is why colon cancer is rare in people under 50 years. Cases people who have less than 50 is often caused by a hereditary disease.
Inherited colon cancer is difficult to diagnose accurately. This is the first consideration when a person has a family history of colon cancer and their families have come from different generations. For example – a man has two uncles and a cousin who has been diagnosed, it will be a family history. With a little 'research into the structure of the patient's family, many more cases of > Colon cancer is preventable and documented.
The two most common types of hereditary colon cancer are not hereditary nonpolyposis colorectal cancer (HNPCC) and familial adenomatous polyposis (FAP). Recently, the gene that causes each of these conditions have been identified and is now a blood test has been developed that tells you if you have inherited the disease. Thanks to these blood tests, a person who had inherited the disease can begin testing for colon> Cancer in an age earlier than most people. These first tests provide doctors to take the disease at an early stage, when they are most discussed. It also allows a doctor to determine whether a course of chemoprevention is appropriate or if other prevention strategies are most appropriate.
Hereditary non-polyposis colon cancer occurs when the genetic damage that interferes with the repair of cells. HNPCC causes about 5% of all diagnoses of colon cancer, but can causeother tumors as well. HNPCC can cause cancer of the urinary tract (kidneys, bladder or ureter), the female reproductive system (uterus, endometrium, or ovary), or the rest of the gastrointestinal tract (stomach, small intestine, or pancreas). A person with HNPCC has a 80% probability of developing cancer of the colon. Even with these high risk, regular examinations and cancer screenings can save lives by preventing or catching cancer at an early stage.
Familyadenomatous polyposis causes hundreds, even thousands of polyps develop in the digestive system of a person. As a person with FAP begins developing colon polyps at a young age – he or she often develops colon cancer at the age of 40 years, ten years earlier than most doctors, also started screening for it. Therefore, it is recommended that people with a family history of blood to check FAP will.
Not much is known about young people represent. Some forms of juvenile delinquencypose is hereditary, but there is a commercial genetic test yet. The only evidence available is used only for research purposes. Juvenile polyps are often the cause of the colon and small intestine. If symptoms are present, are often caused by polyps in the colon. Surgery is often the recommended treatment in such cases.
Peutz-Jegher is a genetic disease that causes intestinal polyps and freckles on the skin ofmouth. There are cases of Peutz-Jegher has freckles developing skin cancer. The greatest risk comes from the colon polyps in the colon. These polyps are usually found in the intestine and can become so large that they cause an intestinal blockage. About half of patients Peutz-Jegher require surgery for a block in an age of 20 years. Peutz-Jegher's was also associated with an increased risk of other cancers, and it is recommendedAll patients begin Puetz-Jegher projections of cancer at a younger age than the general population.