Peritoneal mesothelioma cancer
Cancer of the lining of the abdominal cavity is called peritoneal mesothelioma. It is not as common as pleural form, comprises about one-fifth to one third of cases diagnosed with mesothelioma. The report of the surveillance, epidemiology and end results (SEER) approach as the number 54.7% 45.3% men and women aged 65-69. The period during which the delay is shorter for patients with asbestos, symptoms that occur after 20-30years of exposure, latency normal pleural mesothelioma is 30-40 years.
Symptoms of peritoneal mesothelioma
When presenting symptoms of peritoneal mesothelioma include Abdominal mass, abdominal pain, enlarged abdomen circumference, abdominal fluid (ascites), enlargement of the abdomen, weight loss, fever, anemia, fatigue and digestive tract. A few months before a diagnosis is confirmed, some patients also complainof symptoms that are nonspecific. Furthermore, peritoneal mesothelioma as a percentage of cases where the health problems of the patient, what other hernia, gallbladder, or pelvic mass.
Doctors who have experience in this field are generally noted that this patient had symptoms for six months to two years before diagnosis. Men often to the doctor complaining of a swelling in the groin (hernia) or around the navel (umbilical hernia). For women the first sign of a problem is often a test of pelvic inflammatory disease when a tumor was discovered.
During the later stages of peritoneal mesothelioma, the symptoms are still an event of thrombosis and intestinal obstruction. There is a marked increase in platelet count for 50% of patients on peritoneal but may be caused by various ailments, so it is really of little help in diagnosis. Low levels of albumin and anemia can also amongSymptoms>.
Peritoneal Mesothelioma Diagnosis
Peritoneal mesothelioma, two clinical types can 'type with the help of CT, the' dry and separate the "wet." And 'classified as "dry" when there are multiple small masses or mass dominant local and generally little or no ascites. The "wet type, diffuse small buttons, not dominant mass and presence of ascites.
If the liquid is found, the process, eliminatingparacentesis but the analysis of this fluid has a limited diagnostic significance. Normally, the definitive diagnosis is achieved by tissue biopsy.
Staging
Since there is no system of organization for peritoneal mesothelioma, the most popular system for the general organization of cancer (TNM) is used. TNM system, the following criteria: (a) the status of the tumor (N) and nodes (M) metastases. Other general categories may also be usefulstage to be determined.
Category one – with a local lesion is completely removed (resected)
Category 2 – the disease has been found in the peritoneal cavity or abdominal body area where there is a risk of tumor removal, as far as possible (debulking)
Category 3 – the disease is in the abdominal cavity and invaded organs like the liver or colon.
Category 4 – the disease extends beyond the stomachcavity
Treatment of peritoneal mesothelioma
Over the past year. The effectiveness of surgery alone or intraperitoneal chemotherapy for the treatment of peritoneal mesothelioma trial, and for this multi-processing is still popular Debulking (cytoreductive) surgery is the removal of all or almost all visible tumors and can be combined with IPHC (Intra-Peritoneal Chemotherapy Hyperthermia), intraperitoneal chemotherapy and radiotherapy.
The elimination of allTumors are not always likely that the prognosis for survival may be consistent with the completeness of cytoreduction of this criterion:
complete cytoreduction
(CC-0): No peritoneal seeding was found in the operational areas
(CC-1): nodules less than 2.5 cm cytoreduction stations after the intra-cavity needed chemotherapy, then the procedure is complete, call.
Incompletecytoreduction
(CC-2) lumps with dimensions of 2.5 to 5 cm to go after cytoreduction
(CC-3) buttons that are larger than 5 cm was found, or there is a concentration unresectable tumor nodules as in any sector of the basin or belly.
Some patients may have spread the disease, where surgery is not considered "potentially cured, palliative treatment can be done by debulking. Please note that treatments should only be administered by specialized personnelmedical peritoneal mesothelioma, a rare malignancy.
A recent clinical study found Alimta (pemetrexed) can function effectively as an agent for the treatment of peritoneal mesothelioma chemotherapy, alone or in combination with cisplatin or platinum-based drugs. This reflects previous findings concerning the drug pemetrexed by pleural mesothelioma.