How Colon Cancer and retinoic acid are interconnected
He recently made progress in finding a cure to treat colon cancer. On October 6, 2006, The Journal of Biological Chemistry published a study on this and the results are surprising. They consist of a molecule that is probably a major cause of colon cancer throughout the world. This molecule is known as the protein C-terminus, or (CTBP). C-terminal protein was found in 85% of cases diagnosedwith colon cancer, this figure is not particularly surprising, and shows without doubt that the administration of this molecule is the answer to most cases of colon cancer in humans.
Blocked by specific molecules that doctors no longer have the mutation that this molecule is induced in Escherichia human gene called adenomatous polyposis, in doing so, would the doctors and their patients with colon cancer and this mutation is actuallyThe first and most important step in the development of colon cancer.
The scenario that we could see a man that a healthy cell, so familial adenomatous polyposis coli gene in humans is not the distribution of C-terminal protein destruction, then the amount of this molecule in the body, the problem arises when adenomatous polyposis coli gene is mutated, because it would no longer be able to control the amount of C-terminalProteins in the body. If this mutation is not stopped, will be the human intestine is unable to function normally.
A result of protein C-terminus is that the normal process in the body that bends of vitamin A was designed for the rest later changed to retinoic acid. If vitamin A is not changed in retinoic acid, which is the normal process, your body will be able to produce normal cells, because retinoic acid is actuallythe task of determining which types of cells in the body shape and how long these cells remain in the body.
If the body is an excessive amount of protein C-terminus, can be dangerous because it can lead to cancer of the colon was maintained. The reason is because the body will be able to obtain a sufficient amount of retinoic acid, they really need. Thus, when the mutation of familial adenomatous polyposis coli culprit, C-terminalProteins are removed, so the result is the restoration of normal function in the gut, not because the size of retinoic acid production is of the utmost importance to have ceased to be back to normal.
But the drawback of this otherwise positive turning point is that the C-terminus of proteins with an unknown agent to stop or remove from the body. Researchers are now studying some substances that the body can help stop the actions of the C-terminal binding proteinbefore it represents a greater threat to the human body.
Understand the importance of retinoic acid and its role in the prevention of mutations in the adenomatous polyposis coli gene in the human body is important. By understanding the functions of our body is better we can protect against cancer of the colon and also ensure our health.
This particular survey is really a necessary pause, because now the colon canceris one of the cancers that actually kills people, especially in America. This type of cancer is also one of the most common types in the Western world.
Note: This article may be freely reproduced as long as the resource page at the end of this article is included and all links and must be active / available at no syntax changes.