About Colorectal Cancer
Of the colon or colorectal cancer is cancer of the colon, the last part of the digestive system of vertebrates. We start with the uncontrolled expansion of epithelial cells that line the inside of the colon. Colon in most mammals is the last part of the gastrointestinal tract. Its main task is to keep water and other materials from solid waste before being expelled from the body.
Is observed that the majority of colon cancer starts with polyps, which are hyperplastic masses. But this small balloon structures may be subjected to a sequence of changes in pre-tumorigenic (ie tubular adenoma) and ultimately metastatic cancer (eg adenocarcinoma of the colon-rectum) growth.
For many years, cancer of the colon cancer is still one of the most frequently diagnosed cancers in the world, with hundreds of thousands of new cases diagnosed each year. Increasing> The incidence of cancer is often accompanied by a high mortality rate. Colorectal cancer is among the leading cause of cancer deaths around the world.
There are a number of risk factors associated with the work of developing cancer of the colon-rectum. Age as one of them. Increases the risk of cancer with age. And men have a higher risk than women. Another group at high risk of colon cancer are people with a personal or familyby inherited genetic mutations (HNPCC: hereditary colon cancer associated with polyposis or FAP: familial adenomatous polyposis). People with inflammatory bowel disease have an increased risk of developing kolonkanker occur.
Other important risk factors including obesity, the extreme consumption of red meat, higher fat diet, a diet low in calcium, vitamin D, selenium and folic acid, an insufficient dose of fruit and vegetables , lack of exercise, smoking, and aging of the immune systemsystem. On the contrary, studies have shown that steroidal anti-inflammatory drugs (NSAIDs) like aspirin and ibuprofen, estrogen-containing medications and cholesterol-lowering drugs may protect against colon cancer. These drugs are not allowed at this point in time, as an alternative to prevention.
While many symptoms may indicate the presence of these tumors, many of these symptoms are not unique to colon cancer, and is in factvery similar to normal diseases and other diseases. These symptoms may appear suddenly or may increase gradually over time. Symptoms include changes in stool, persistent diarrhea, constipation, intestinal obstruction total (with extreme pain), bloody stools, sudden or chronic stomach cramps and pain, to name just a few short .
Surgery is the treatment even more powerful if the tumor is not aggressive and metastasize. Itdone by removing the tumor along with part of the normal intestinal tissue and nearby lymph nodes.
Other types of treatments include chemotherapy, radiotherapy and immunotherapy. Individual or combinatorial therapies may occur depending on the physical condition of the patient and the stage of disease.